Kallikrein 6 antibody (AA 227-244)

Catalog No. ABIN2624595

The Rabbit Polyclonal anti-Kallikrein 6 antibody has been validated for WB, IHC, ICC and IHC (p). It is suitable to detect Kallikrein 6 in samples from Human and Monkey.

Quick Overview for Kallikrein 6 antibody (AA 227-244) (ABIN2624595)

Target: Kallikrein 6 (KLK6)

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Kallikrein 6 Antibody

Binding Specificity: AA 227-244

Specificity: In fluids, highest levels found in milk of lactating women followed by cerebrospinal fluid, nipple aspirate fluid and breast cyst fluid. Also found in serum, seminal plasma and some amniotic fluids and breast tumor cytosolic extracts. Not detected in urine. At the tissue level, highest concentrations found in glandular tissues such as salivary glands followed by lung, colon, fallopian tube, placenta, breast, pituitary and kidney. Not detected in skin, spleen, bone, thyroid, heart, ureter, liver, muscle, endometrium, testis, pancreas, seminal vesicle, ovary, adrenals and prostate. In brain, detected in gray matter neurons (at protein level). Colocalizes with pathological inclusions such as Lewy bodies and glial cytoplasmic inclusions. Overexpressed in primary breast tumors but not expressed in metastatic tumors. .

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 6(227-244aa YTNVCRYTNWIQKTIQAK).

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for Kallikrein 6

Target: Kallikrein 6 (KLK6)

Alternative Name: KLK6 / Kallikrein 6

Background: Name/Gene ID: KLK6
Subfamily: Serine S1
Family: Protease

Synonyms: KLK6, Bssp, HK6, Kallikrein-related peptidase 6, Kallikrein 6 (neurosin, zyme), Neurosin, Protease, serine, 18, Protease M, PRSS9, Serine protease 9, Zyme, Serine protease 18, Kallikrein 6, Kallikrein-6, PRSS18, SP59

Gene ID: 5653

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling