MERTK antibody (AA 132-148)

Catalog No. ABIN2625344

This Rabbit Polyclonal antibody specifically detects MERTK in WB. It exhibits reactivity toward Human, Monkey, Cow and Rabbit.

Quick Overview for MERTK antibody (AA 132-148) (ABIN2625344)

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Reactivity: Human, Monkey, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MERTK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MERTK Antibody

Binding Specificity: AA 132-148

Specificity: Not expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines. Highly expressed in testis, ovary, prostate, lung, and kidney, with lower expression in spleen, small intestine, colon, and liver.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MERTK(132-148aa KDGKELLGAHHAITQFY), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for MERTK

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Alternative Name: MER / MERTK

Background: Name/Gene ID: MERTK
Subfamily: Axl
Family: Protein Kinase

Synonyms: MERTK, Eyk, MER, MER receptor tyrosine kinase, Nyk, Proto-oncogene c-Mer, RP38, STK kinase, C-mer, Receptor tyrosine kinase MerTK, Tyrosine-protein kinase Mer

Gene ID: 10461

Pathways: RTK Signaling