Nicastrin antibody (AA 72-88)

Catalog No. ABIN2625956

This Rabbit Polyclonal antibody specifically detects Nicastrin in WB. It exhibits reactivity toward Human, Rat, Cow, Pig, Bat and Horse.

Quick Overview for Nicastrin antibody (AA 72-88) (ABIN2625956)

Target: Nicastrin (NCSTN)

Reactivity: Human, Rat, Cow, Pig, Bat, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nicastrin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Nicastrin Antibody

Binding Specificity: AA 72-88

Specificity: Widely expressed.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Nicastrin(72-88aa VIHVVEKEEDLQWVLTD), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for Nicastrin

Target: Nicastrin (NCSTN)

Alternative Name: NCSTN / Nicastrin

Background: Name/Gene ID: NCSTN
Family: Protease

Synonyms: NCSTN, Anterior pharynx-defective 2, ATAG1874, KIAA0253, Nicastrin, APH2, RP11-517F10.1

Gene ID: 23385

Pathways: Notch Signaling, Neurotrophin Signaling Pathway