RRM2B antibody (AA 318-332)

Catalog No. ABIN2627773

The Rabbit Polyclonal anti-RRM2B antibody (ABIN2627773) specifically detects RRM2B in WB. The antibody is reactive with Human, Rat, Mouse, Monkey, Cow, Rabbit, Horse, Pig, Bat, Xenopus laevis, Chicken and Sheep samples.

Quick Overview for RRM2B antibody (AA 318-332) (ABIN2627773)

Target: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Reactivity: Human, Rat, Mouse, Monkey, Cow, Rabbit, Horse, Pig, Bat, Xenopus laevis, Chicken, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRM2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RRM2B Antibody

Binding Specificity: AA 318-332

Specificity: Widely expressed at a high level in skeletal muscle and at a weak level in thymus. Expressed in epithelial dysplasias and squamous cell carcinoma. .

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human p53R2(318-332aa EGKTNFFEKRVSEYQ), identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for RRM2B

Target: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Alternative Name: RRM2B

Background: Name/Gene ID: RRM2B
Family: RIBONUCLEOTIDE REDUCTASE

Synonyms: RRM2B, MTDPS8A, MTDPS8B, p53R2, PEOA5

Gene ID: 50484

Pathways: p53 Signaling, Negative Regulation of intrinsic apoptotic Signaling