RRM2B antibody (AA 318-332)
Quick Overview for RRM2B antibody (AA 318-332) (ABIN2627773)
Target
See all RRM2B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 318-332
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Specificity
- Widely expressed at a high level in skeletal muscle and at a weak level in thymus. Expressed in epithelial dysplasias and squamous cell carcinoma. .
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Cross-Reactivity (Details)
- No cross reactivity with other proteins.
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Purification
- Immunogen affinity purified
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Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human p53R2(318-332aa EGKTNFFEKRVSEYQ), identical to the related rat and mouse sequences.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Distilled water
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Concentration
- Lot specific
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Buffer
- Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.
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Preservative
- Sodium azide, Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
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- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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Alternative Name
- RRM2B
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Background
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Name/Gene ID: RRM2B
Family: RIBONUCLEOTIDE REDUCTASE
Synonyms: RRM2B, MTDPS8A, MTDPS8B, p53R2, PEOA5 -
Gene ID
- 50484
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Pathways
- p53 Signaling, Negative Regulation of intrinsic apoptotic Signaling
Target
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