CKM antibody

Catalog No. ABIN263586

The Mouse Monoclonal anti-CKM antibody (Clone 027-17186) (ABIN263586) specifically detects CKM in EIA. The antibody is reactive with Human samples.

Quick Overview for CKM antibody (ABIN263586)

Target: CKM (Creatine Kinase, Muscle (CKM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CKM antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: 027-17186

Product Details anti-CKM Antibody

Specificity: This antibody reacts to Creatine Kinase MM. Cross-reactivity: CK-MB:50 % CK-BB:<1 %Aff. Const.:3 x 10e9 L/m

Characteristics: Synonyms: Creatine kinase M-type, Creatine kinase M chain, M-CK, CKM, Creatine kinase MM

Purification: Protein A chromatography

Purity: > 90 % pure (SDS-PAGE)

Immunogen: Purified human CK-MM

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 4.22mg/mL (OD280nm, E0.1% = 1.4)

Buffer: 10 mM Phosphate, pH 7.4 containing 150 mM Sodium chloride and 0.09 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one week or (in aliquots) at -40 °C for longer. If aliquoted for long term storage, fill volume should be equal to or greater than 50% of thenominal fill volume of the vial used. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CKM

Target: CKM (Creatine Kinase, Muscle (CKM))

Alternative Name: CKMM

Background: Creatine Kinase MM (CK-MM) is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.Synonyms: CKM, Creatine kinase M chain, Creatine kinase M-type, Creatine kinase MM, M-CK

Gene ID: 1158

UniProt: P06732