Cyclin A1 antibody
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- Target See all Cyclin A1 (CCNA1) Antibodies
- Cyclin A1 (CCNA1)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Cyclin A1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- The antibody detects endogenous levels of Cyclin A1 protein(region surrounding Arg436).
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- The antibody was purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen
- Purity
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product CCNA1 Primary Antibody
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- Application Notes
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Cyclin A1 (CCNA1)
- Alternative Name
- Cyclin A1 (CCNA1 Products)
- Synonyms
- fd14f08 antibody, wu:fd14f08 antibody, wu:fi20d12 antibody, zgc:111869 antibody, MGC81965 antibody, cyclin-A1 antibody, CCNA1 antibody, MGC132235 antibody, cyclin-A1-2 antibody, Cyclin-A1 antibody, ccna1 antibody, cyclin A1 antibody, cyclin A1 L homeolog antibody, CYCLIN A1;2 antibody, cyclin A1 S homeolog antibody, CCNA1 antibody, ccna1 antibody, ccna1.L antibody, CYCA1;2 antibody, Ccna1 antibody, ccna1.S antibody
- Background
- Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34.Synonyms: CCNA1, Cyclin-A1
- Molecular Weight
- approx. 52 kDa
- Gene ID
- 8900
- NCBI Accession
- NP_001104515
- UniProt
- P78396
- Pathways
- Apoptosis, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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