SCGB2A1
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
Biotin
Application Notes
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
LPHC antibody, LPNC antibody, MGB2 antibody, UGB3 antibody, Psbp1 antibody, secretoglobin family 2A member 1 antibody, secretoglobin, family 2A, member 1 antibody, SCGB2A1 antibody, Scgb2a1 antibody
Background
Secretoglobins (also called lipophilins or mammaglobins) are small secreted proteins of ndocrine-responsive organs and mucosal epithelia that form multimeric complexes and correlate with the development of various human cancers. Lipophilin A and Lipophilin B are orthologs of prostatein estramustine- binding protein), the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin A, also designated LIPA, LPHA and secretoglobin, family 1D, member 1 (SCGB1D1), is a component of a heterodimeric molecule present in human tears. Lipophilin B, also designated LIPB, LPHB and secretoglobin, family 1D, member 2 (SCGB1D2), mRNA can be overexpressed in breast tumors and shows a high degree of correlation with the mRNA expression profile of mammaglobin. Histological detection in breast tissue of Mammaglobin A, also designated MGB1 and secretoglobin, family 2A, member 2 (SCGB2A2) and Mammaglobin B, also designated MGB2, Lipophilin C, LPHC, UGB3 and SCGB2A2, is a reliable diagnostic marker for breast tumors.Synonyms: LIPHC, Lacryglobin, Lipophilin-C, Mammaglobin-2, Mammaglobin-B, Secretoglobin family 2A member 1