SCGB2A1 antibody

Catalog No. ABIN265511

The Rabbit Polyclonal anti-SCGB2A1 antibody is suitable to detect SCGB2A1 in samples from Human. It has been validated for WB, IF and IHC (p).

Quick Overview for SCGB2A1 antibody (ABIN265511)

Target: SCGB2A1 (Secretoglobin, Family 2A, Member 1 (SCGB2A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCGB2A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SCGB2A1 Antibody

Specificity: This antibody detects endogenous levels of Mammaglobin B protein. (region surrounding Lys23)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SCGB2A1

Target: SCGB2A1 (Secretoglobin, Family 2A, Member 1 (SCGB2A1))

Alternative Name: SCGB2A1 / Mammaglobin B

Background: Secretoglobins (also called lipophilins or mammaglobins) are small secreted proteins of ndocrine-responsive organs and mucosal epithelia that form multimeric complexes and correlate with the development of various human cancers. Lipophilin A and Lipophilin B are orthologs of prostatein estramustine- binding protein), the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin A, also designated LIPA, LPHA and secretoglobin, family 1D, member 1 (SCGB1D1), is a component of a heterodimeric molecule present in human tears. Lipophilin B, also designated LIPB, LPHB and secretoglobin, family 1D, member 2 (SCGB1D2), mRNA can be overexpressed in breast tumors and shows a high degree of correlation with the mRNA expression profile of mammaglobin. Histological detection in breast tissue of Mammaglobin A, also designated MGB1 and secretoglobin, family 2A, member 2 (SCGB2A2) and Mammaglobin B, also designated MGB2, Lipophilin C, LPHC, UGB3 and SCGB2A2, is a reliable diagnostic marker for breast tumors.Synonyms: LIPHC, Lacryglobin, Lipophilin-C, Mammaglobin-2, Mammaglobin-B, Secretoglobin family 2A member 1

Molecular Weight: approx. 15 kDa

Gene ID: 4246

NCBI Accession: NP_002398

UniProt: O75556