CD4 antibody (Alexa Fluor 488)

Catalog No. ABIN2657424

This Rat Monoclonal antibody specifically detects CD4 in FACS and ICFC. It exhibits reactivity toward Mouse.

Quick Overview for CD4 antibody (Alexa Fluor 488) (ABIN2657424)

Target: CD4

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Clone: GK1-5

Product Details anti-CD4 Antibody (Alexa Fluor 488)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events