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FLT3 antibody (APC)

This anti-FLT3 antibody is a Rat Monoclonal antibody detecting FLT3 in WB, FACS, ICC and BR. Suitable for Mouse.
Catalog No. ABIN2658479

Quick Overview for FLT3 antibody (APC) (ABIN2658479)

Target

See all FLT3 Antibodies
FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Reactivity

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Mouse

Host

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Rat

Clonality

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Monoclonal

Conjugate

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This FLT3 antibody is conjugated to APC

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Blocking Reagent (BR)

Clone

A2F10
  • Purification

    The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

    Isotype

    IgG2a kappa
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    0.2 mg/mL

    Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Protect from prolonged exposure to light. Do not freeze.

    Storage

    4 °C

    Storage Comment

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

    Alternative Name

    CD135

    Background

    CD135, also known as Flk-2, Flt3, and Ly-72, is a type III tyrosine kinase receptor. It is expressed on early B lymphoid lineage cells in bone marrow, on primitive myeloid progenitors within the BM CD34+ cell population. Ligation of Flk-2 with Flt3 ligand regulates the growth of hematopoietic stem cells and promotes the survival of primitive hematopoietic progenitor cells with myeloid as well as B lymphoid potential. It was reported that the receptor tyrosine kinase Flt3 is required for dendritic cell development. Combined signaling through interleukin-7 receptors and Flt3 selectively promotes B-cell commitment and differentiation from uncommitted murine bone marrow progenitor cells.

    Pathways

    RTK Signaling
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