IL-1 beta antibody (Biotin)

Catalog No. ABIN2660776

The Goat Polyclonal anti-IL-1 beta antibody has been validated for FACS. It is suitable to detect IL-1 beta in samples from Human.

Quick Overview for IL-1 beta antibody (Biotin) (ABIN2660776)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This IL-1 beta antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: Poly5174

Product Details anti-IL-1 beta Antibody (Biotin)

Purification: The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Alternative Name: IL-1beta

Background: IL-1 refers to two proteins, IL-1α and IL-1β, which are the products of distinct genes, but which are recognized by the same cell surface receptors. IL-1β is a potent immunomodulator which mediates a wide range of immune and inflammatory responses, including the activation of B and T cells.

Pathways: NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome