GP5 antibody (PE)
Quick Overview for GP5 antibody (PE) (ABIN2662644)
Target
See all GP5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
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Storage
- 4 °C
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Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- GP5 (Glycoprotein V (Platelet) (GP5))
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Alternative Name
- CD42d
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Background
- CD42d is an 83 kD surface glycoprotein that non-covalently associates with GPIb and GPIX to form a receptor complex for von Willebrand factor on megakaryocytes and resting platelets. Binding sites for von Willebrand factor and thrombin have been localized to the GPIba chain of the GPI-b-V-IX complex. Platelet activation with thrombin cleaves the GPI-b-V-IX complex to release a 69 kD soluble fragment. Presence of the GPI-b-V-IX complex is important in Bernard-Soulier syndrome, a rare bleeding disorder.
Target
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