IL2 Receptor beta antibody (Interleukin 2 Receptor, beta) (PE)

Details for Product anti-IL2RB Antibody No. ABIN2662984, Supplier: Log in to see
Antigen
  • IL2RB
  • il-2rb
  • CD122
  • IL15RB
  • P70-75
  • IL2RBC
  • IL-15Rbeta
  • IL15Rbeta
  • Il-2/15Rbeta
  • Il-2Rbeta
  • p70
  • interleukin 2 receptor subunit beta
  • interleukin-2 receptor subunit beta
  • interleukin 2 receptor, beta
  • interleukin 2 receptor, beta chain
  • IL2RB
  • LOC510185
  • il2rb
  • Il2rb
Alternatives
anti-Human IL2 Receptor beta antibody for Flow Cytometry
Reactivity
Chemical, Human
215
180
82
28
10
1
1
Host
Mouse
142
124
69
Clonality (Clone)
Monoclonal ()
Conjugate
This IL2 Receptor beta antibody is conjugated to PE
30
28
20
14
6
5
4
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
184
127
66
62
41
26
14
14
11
10
7
4
4
3
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Clone TU27
Isotype IgG1 kappa
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Plasmids, Primers & others Plasmids, Primers & others IL2 Receptor beta products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD122 (IL2RB Antibody Abstract)
Target Type Chemical
Background CD122 is a 70-75 kD type I transmembrane glycoprotein and member of the Ig superfamily. It is IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. CD122 is constitutively expressed by NK cells and at lower levels by a subset of T cells. Its expression is upregulated upon activation. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation.
Pathways JAK-STAT Signaling, Growth Factor Binding
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.
Supplier Images
Flow Cytometry (FACS) image for anti-Interleukin 2 Receptor, beta (IL2RB) antibody (PE) (ABIN2662984) anti-Interleukin 2 Receptor, beta (IL2RB) antibody (PE)
Background publications Suzuki, Kündig, Furlonger, Wakeham, Timms, Matsuyama, Schmits, Simard, Ohashi, Griesser: "Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta." in: Science (New York, N.Y.), Vol. 268, Issue 5216, pp. 1472-6, 1995 (PubMed).

Minami, Kono, Miyazaki, Taniguchi: "The IL-2 receptor complex: its structure, function, and target genes." in: Annual review of immunology, Vol. 11, pp. 245-68, 1993 (PubMed).

Takeshita, Goto, Tada, Nagata, Asao, Sugamura: "Monoclonal antibody defining a molecule possibly identical to the p75 subunit of interleukin 2 receptor." in: The Journal of experimental medicine, Vol. 169, Issue 4, pp. 1323-32, 1989 (PubMed).

Did you look for something else?