LTBR antibody (PE)

Catalog No. ABIN2663836

The Rat Monoclonal anti-LTBR antibody is suitable to detect LTBR in samples from Mouse. It has been validated for FACS, IHC and IP.

Quick Overview for LTBR antibody (PE) (ABIN2663836)

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This LTBR antibody is conjugated to PE

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: 5G11

Product Details anti-LTBR Antibody (PE)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for LTBR

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Alternative Name: Lymphotoxin beta Receptor

Background: LTβR is a type I transmembrane glycoprotein and member of the TNF receptor superfamily. It is a 61 KDa receptor for the mouse LTα1β2 and LIGHT. Northern blot analysis of tissues from adult mice showed that expression levels of LTβR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. It was reported that LTβR is expressed on stromal cells, monocytes, and certain embryonic epithelial layers. LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis.

Pathways: NF-kappaB Signaling