LTBR antibody (AA 31-227)

Catalog No. ABIN7193282

Product Details anti-LTBR Antibody

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Binding Specificity: AA 31-227

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This LTBR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human LTBR (AA: extra 31-227) expressed in E. coli.

Clone: 1D1C5C8

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for LTBR

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Alternative Name: LTBR (LTBR Products)

Synonyms: AI256028 antibody, CD18 antibody, LTbetaR antibody, Ltar antibody, TNF-R-III antibody, TNFCR antibody, TNFR-RP antibody, TNFR2-RP antibody, TNFRrp antibody, Tnfbr antibody, Tnfrsf3 antibody, D12S370 antibody, LT-BETA-R antibody, TNFR3 antibody, TNFRSF3 antibody, lymphotoxin beta receptor antibody, lymphotoxin B receptor antibody, Ltbr antibody, LTBR antibody

Background:

Description: This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Aliases: TNFCR, TNFR3, D12S370, TNFR-RP, TNFRSF3, TNFR2-RP, LT-BETA-R, TNF-R-III

Molecular Weight: 46.7 kDa

Gene ID: 4055

Pathways: NF-kappaB Signaling