IL16 antibody (AA 615-630)

Catalog No. ABIN2665114

Product Details anti-IL16 Antibody

Target: IL16 (Interleukin 16 (IL16))

Binding Specificity: AA 615-630

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL16 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Cross-Reactivity: Mouse (Murine)

Purification: The antibody was purified by affinity chromatography.

Immunogen: AA 615-630 (RRKSLQSKETTAAGDS) of IL-16

Clone: 14-1

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for IL16

Target: IL16 (Interleukin 16 (IL16))

Alternative Name: IL-16 (IL16 Products)

Synonyms: IL16 antibody, LCF antibody, NIL16 antibody, PRIL16 antibody, prIL-16 antibody, mKIAA4048 antibody, IL-16 antibody, interleukin 16 antibody, IL16 antibody, Il16 antibody

Background: Interleukin-16 is a proinflammatory cytokine synthesized as a 68 kD precursor molecule (pro-IL-16). After cleavage of pro-IL-16 by caspase-3, IL-16 is released as a 12 kD protein, but its biologic activities are exerted by a tetramer. IL-16 is a chemoattractant for CD4+ T cells, monocytes, and eosinophils. On T cells, IL-16 upregulates CD25 and class II expression, and also inhibits HIV-1 replication in vitro by repressing the transcription of the HIV-1 long terminal repeat. IL-16 is expressed by lymphocytes, macrophages, eosinophils, mast cells, epithelial cells, and fibroblasts. CD4 and CD9 are the receptors of IL-16.