PTBP1 antibody

Catalog No. ABIN2665344

This Mouse Monoclonal antibody specifically detects PTBP1 in FACS. It exhibits reactivity toward Human.

Quick Overview for PTBP1 antibody (ABIN2665344)

Target: PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTBP1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 3H7

Product Details anti-PTBP1 Antibody

Characteristics: The 3H7 monoclonal antibody recognizes human PTBP1 also known as Polypyrimidine tract binding protein 1, Heterogeneous nuclear ribonucleoprotein I, and 57 kD RNA-binding protein. PTBP1 is a ubiquitously expressed nuclear protein with a predicted molecular weight approximately 59.6 kD. The polypyrimidine tract binding protein (PTB) is an important regulator of alternative splicing that also affects mRNA localization, stabilization, polyadenylation, and translation. PTBP1 has been shown to interact with FUS, Caspase3, PKCa, Raver1, and HnRNP-L protein. The PTB gene contains 15 exons and spans 13.5 kb. The 3H7 antibody has been shown to be useful for Western blotting.

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for PTBP1

Target: PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

Alternative Name: PTBP1

Pathways: Regulation of Muscle Cell Differentiation