AGO1 antibody (N-Term)

Catalog No. ABIN2668226

Cited in 2+ publications. The Rat Monoclonal anti-AGO1 antibody (Clone 4B8) (ABIN2668226) specifically detects AGO1 in WB and IP. The antibody is reactive with Human samples.

Quick Overview for AGO1 antibody (N-Term) (ABIN2668226)

Target: AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This AGO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 4B8

Product Details anti-AGO1 Antibody

Binding Specificity: N-Term

Purification: Protein G Chromatography

Immunogen: This Ago1 antibody was raised against a peptide from the N-terminus of human Argonaute 1 (Ago1) protein.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -80 °C

Storage Comment: Antibodies in solution can be stored at -80 °C for 2 years.

Expiry Date: 6 months

References for anti-AGO1 antibody (ABIN2668226)

Beitzinger, Peters, Zhu, Kremmer, Meister: "Identification of human microRNA targets from isolated argonaute protein complexes." in: RNA biology, Vol. 4, Issue 2, pp. 76-84, (2007) (PubMed).

Höck, Weinmann, Ender, Rüdel, Kremmer, Raabe, Urlaub, Meister: "Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells." in: EMBO reports, Vol. 8, Issue 11, pp. 1052-60, (2007) (PubMed).

Target Details for AGO1

Target: AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))

Alternative Name: Ago1

Molecular Weight: 100 kDa

Gene ID: 26523

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Transport, Regulation of Actin Filament Polymerization, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization