DNMT3A antibody

Catalog No. ABIN2668262

Cited in 3+ publications. The Mouse Monoclonal anti-DNMT3A antibody (Clone 64B1446) (ABIN2668262) specifically detects DNMT3A in WB and ChIP. The antibody is reactive with Human and Mouse samples.

Quick Overview for DNMT3A antibody (ABIN2668262)

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This DNMT3A antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Clone: 64B1446

Product Details anti-DNMT3A Antibody

Purification: Affinity Purified

Immunogen: This DNMT3A antibody was raised against a full-length protein corresponding to mouse DNMT3A.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -80 °C

Storage Comment: Antibodies in solution can be stored at -80 °C for 2 years.

Expiry Date: 6 months

References for anti-DNMT3A antibody (ABIN2668262)

Petell, Alabdi, He, San Miguel, Rose, Gowher: "An epigenetic switch regulates de novo DNA methylation at a subset of pluripotency gene enhancers during embryonic stem cell differentiation." in: Nucleic acids research, Vol. 44, Issue 16, pp. 7605-17, (2016) (PubMed).

Karius, Schnekenburger, Ghelfi, Walter, Dicato, Diederich: "Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines." in: Biochemical pharmacology, Vol. 81, Issue 11, pp. 1329-42, (2011) (PubMed).

Saito, Kato, Hiraoka, Horii, Suzuki, Higashi, Kaji, Kondo, Yamamoto: "DNA methylation of colon mucosa in ulcerative colitis patients: correlation with inflammatory status." in: Inflammatory bowel diseases, Vol. 17, Issue 9, pp. 1955-65, (2011) (PubMed).

Target Details for DNMT3A

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Alternative Name: DNMT3A

Molecular Weight: 116 kDa

Gene ID: 1788