ASH2L antibody (N-Term)

Catalog No. ABIN2668901

Cited in 1 publication. The Rat Monoclonal anti-ASH2L antibody (Clone 4C5) (ABIN2668901) specifically detects ASH2L in WB, IHC, IF, ICC and IP. The antibody is reactive with Human samples.

Quick Overview for ASH2L antibody (N-Term) (ABIN2668901)

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This ASH2L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: 4C5

Product Details anti-ASH2L Antibody

Binding Specificity: N-Term

Purpose: ASH2L antibody (mAb) (Clone 4C5)

Purification: Protein G Chromatography

Immunogen: This antibody was raised against a recombinant protein corresponding to the N-terminal region of human ASH2L.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

References for anti-ASH2L antibody (ABIN2668901)

Lüscher-Firzlaff, Gawlista, Vervoorts, Kapelle, Braunschweig, Walsemann, Rodgarkia-Schamberger, Schuchlautz, Dreschers, Kremmer, Lilischkis, Cerni, Wellmann, Lüscher: "The human trithorax protein hASH2 functions as an oncoprotein." in: Cancer research, Vol. 68, Issue 3, pp. 749-58, (2008) (PubMed).

Target Details for ASH2L

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Alternative Name: ASH2L

Background: ASH2L (absent, small, or homeotic)-like (Drosophila) is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

Molecular Weight: 85 kDa

Gene ID: 9070

NCBI Accession: NP_004665