STAT5 A/B antibody (pSer726, pSer731)

Catalog No. ABIN2668939

The Rabbit Polyclonal anti-STAT5 A/B antibody is suitable to detect STAT5 A/B in samples from Human. It has been validated for WB and DB.

Quick Overview for STAT5 A/B antibody (pSer726, pSer731) (ABIN2668939)

Target: STAT5 A/B

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT5 A/B antibody is un-conjugated

Application: Western Blotting (WB), Dot Blot (DB)

Product Details anti-STAT5 A/B Antibody

Binding Specificity: pSer726, pSer731

Purpose: STAT5A/B phospho Ser726/Ser731 antibody (pAb)

Purification: Affinity Purified

Immunogen: This STAT5A/B phospho Ser726/Ser731 antibody was raised against a peptide containing phospho Ser726 of human STAT5A. Human STAT5B shares the identical sequence surrounding Ser731.

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2,000 dilution

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for STAT5 A/B

Target: STAT5 A/B

Alternative Name: STAT5A/B

Background: STAT5A/B (signal transducer and activator of transcription 5) is a member of the STAT family of transcription factors. STATs undergo serine and tyrosine phosphorylation in response to growth factor or cytokine signaling. This phosphorylation results in dimerization and translocation of STAT proteins to the nucleus. The STAT5 protein is expressed in most cell types and is activated by multiple cytokines and growth factors including: IFNa, IL-10, IL-6, IL-11, IL-12, IL-2, EGF, among others.

Molecular Weight: 92 kDa

Gene ID: 6776