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Menin antibody (AA 392-554)

MEN1 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 7D3E10 unconjugated
Catalog No. ABIN2682998
  • Target See all Menin (MEN1) Antibodies
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 392-554
    Reactivity
    • 77
    • 32
    • 24
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 70
    • 5
    • 2
    • 1
    Mouse
    Clonality
    • 71
    • 7
    Monoclonal
    Conjugate
    • 39
    • 7
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Menin antibody is un-conjugated
    Application
    • 57
    • 38
    • 22
    • 18
    • 13
    • 13
    • 11
    • 8
    • 8
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human MEN1 (AA: 392-554) expressed in E. coli.
    Clone
    7D3E10
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Alternative Name
    MEN1 (MEN1 Products)
    Synonyms
    MEAI antibody, SCG2 antibody, menin antibody, meai antibody, scg2 antibody, AW045611 antibody, menin 1 antibody, menin 1 L homeolog antibody, multiple endocrine neoplasia I antibody, multiple endocrine neoplasia 1 antibody, MEN1 antibody, men1 antibody, men1.L antibody, Men1 antibody
    Background

    Description: This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.

    Aliases: MEAI, SCG2

    Molecular Weight
    68 kDa
    Gene ID
    4221
    HGNC
    4221
    Pathways
    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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