ROR2 antibody (AA 59-155)
Quick Overview for ROR2 antibody (AA 59-155) (ABIN2683012)
Target
See all ROR2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 59-155
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Purpose
- ROR2 Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human ROR2 (AA: 59-155) expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
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Alternative Name
- ROR2
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Background
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The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.
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Molecular Weight
- 104.8 kDa
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UniProt
- Q01974
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Pathways
- RTK Signaling, WNT Signaling
Target
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