LAMP1 antibody

Catalog No. ABIN2688884

This Mouse Monoclonal antibody specifically detects LAMP1 in ICS and FM. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for LAMP1 antibody (ABIN2688884)

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LAMP1 antibody is un-conjugated

Application: Intracellular Staining (ICS), Fluorescence Microscopy (FM)

Clone: H4A3

Product Details anti-LAMP1 Antibody

Brand: BD Pharmingen™

Characteristics: Reacts with the heavily glycosylated 110 kDa lysosomal-associated membrane protein, LAMP-1. LAMP-1 is a widely expressed intracellular antigen. It is also expressed on the surface of activated platelets, PHA-activated lymphocytes and some tumor cell lines, including U937 and KG1a. LAMP-1 has been shown to be a ligand for E-selectin-mediated cell adhesion. LAMP-1 and LAMP-2 (CD107b) are carriers for poly-N-acetyllactosamines, and are able to display sialyl Le[x] termini. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of permeabilized jurkat cells analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD107a - Purified - Clone H4A3 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-LAMP1 antibody (ABIN2688884)

Febbraio, Silverstein: "Identification and characterization of LAMP-1 as an activation-dependent platelet surface glycoprotein." in: The Journal of biological chemistry, Vol. 265, Issue 30, pp. 18531-7, (1990) (PubMed).

Target Details for LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Alternative Name: CD107a

Background: Synonyms: LAMP-1

Pathways: Autophagy