CXCR1 antibody

Catalog No. ABIN2689039

Cited in 2+ publications. The Mouse Monoclonal anti-CXCR1 antibody (Clone 5A12) (ABIN2689039) specifically detects CXCR1 in FACS and IF. The antibody is reactive with Human samples.

Quick Overview for CXCR1 antibody (ABIN2689039)

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CXCR1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 5A12

Product Details anti-CXCR1 Antibody

Characteristics: Reacts with Interleukin-8 receptor A (IL-8RA), a G protein-linked seven transmembrane domain protein, expressed on monocytes and granulocytes. It is also expressed on a subset of T cells. Both IL-8RA and IL-8RB are high affinity receptors for IL-8. IL-8 is an inflammatory cytokine which induces chemotaxis of neutrophils, basophils and T lymphocytes. IL-8RA and IL-8RB were first clustered as CD128a and CD128b, respectively in the VIIth HLDA workshop, and then were re-clustered as CD181 and CD182, respectively in the VIIIth HLDA workshop. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood granulocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

BD Pharmingen™ Purified Mouse Anti-Human CD181 - Purified - Clone 5A12 - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CXCR1 antibody (ABIN2689039)

Qin, LaRosa, Campbell, Smith-Heath, Kassam, Shi, Zeng, Buthcher, Mackay: "Expression of monocyte chemoattractant protein-1 and interleukin-8 receptors on subsets of T cells: correlation with transendothelial chemotactic potential." in: European journal of immunology, Vol. 26, Issue 3, pp. 640-7, (1996) (PubMed).

Baggiolini, Loetscher, Moser: "Interleukin-8 and the chemokine family." in: International journal of immunopharmacology, Vol. 17, Issue 2, pp. 103-8, (1995) (PubMed).

Target Details for CXCR1

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Alternative Name: CD181

Background: Synonyms: CXCR1, IL-8RA, CD128a

Pathways: cAMP Metabolic Process