ITGA5 antibody

Catalog No. ABIN2689314

There is 1 publication for this product available. The Mouse Monoclonal anti-ITGA5 antibody is suitable to detect ITGA5 in samples from Human and Rabbit. It has been validated for FACS.

Quick Overview for ITGA5 antibody (ABIN2689314)

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reactivity: Human, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA5 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: IIA1

Product Details anti-ITGA5 Antibody

Characteristics: Reacts with the α5 integrin, a dimer of 135/25 kDa, that associates with β1 integrin (CD29) to form VLA-5, a well-established fibronectin receptor that is expressed on many cell types, including fibroblasts, endothelial cells, epithelial cells, platelets, peripheral T cells, the myeloid cell line U937, K562 and some melanoma cell lines. This clone inhibits α5β1/ligand binding, and is useful for studies of the expression and function of this integrin. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of K562 cells analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD49e - Purified - Clone IIA1 - Isotype Mouse IgG1, κ - Reactivity Hu, Rab - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-ITGA5 antibody (ABIN2689314)

Tran Van Nhieu, Isberg: "Bacterial internalization mediated by beta 1 chain integrins is determined by ligand affinity and receptor density." in: The EMBO journal, Vol. 12, Issue 5, pp. 1887-95, (1993) (PubMed).

Target Details for ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Alternative Name: CD49e

Background: Synonyms: Integrin α5 Chain

Pathways: Integrin Complex