CD56 antibody

Catalog No. ABIN2689340

Product Details anti-CD56 Antibody

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD56 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Brand: BD Pharmingen™

Characteristics: Anti-N-CAM-16 monoclonal antibody (clone NCAM16.2) CAMFolio™ recognizes the third extracellular immunoglobulin-like domain common to three molecular weight forms (120-, 140-, and 180-kD) of the neural cell adhesion molecule (N-CAM). The N-CAM glycoprotein is expressed on many different cell and tissue types including natural killer (NK) lymphocytes, a subset of T lymphocytes and interleukin-2 (IL-2)-activated thymocytes, and neural, neuroendocrine, and degenerating of diseased muscle tissue.

BD Pharmingen™ Purified Mouse Anti-Human CD56 - Purified - Clone NCAM16.2 (also known as NCAM 16) - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.2 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: NCAM16-2

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD56 antibody (ABIN2689340)

Zocchi, Vidal, Poggi: "Involvement of CD56/N-CAM molecule in the adhesion of human solid tumor cell lines to endothelial cells." in: Experimental cell research, Vol. 204, Issue 1, pp. 130-5, (1993) (PubMed).

Birdsall, Lane, Ramser, Anderson: "Induction of VCAM-1 and ICAM-1 on human neural cells and mechanisms of mononuclear leukocyte adherence." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 9, pp. 2717-23, (1992) (PubMed).

Doherty, Ashton, Moore, Walsh: "Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels." in: Cell, Vol. 67, Issue 1, pp. 21-33, (1991) (PubMed).

Jin, Hemperly, Lloyd: "Expression of neural cell adhesion molecule in normal and neoplastic human neuroendocrine tissues." in: The American journal of pathology, Vol. 138, Issue 4, pp. 961-9, (1991) (PubMed).

Lanier, Chang, Azuma, Ruitenberg, Hemperly, Phillips: "Molecular and functional analysis of human natural killer cell-associated neural cell adhesion molecule (N-CAM/CD56)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 12, pp. 4421-6, (1991) (PubMed).

Schubert, Zimmermann, Cramer, Starzinski-Powitz: "Lymphocyte antigen Leu-19 as a molecular marker of regeneration in human skeletal muscle." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 1, pp. 307-11, (1989) (PubMed).

Lanier, Testi, Bindl, Phillips: "Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule." in: The Journal of experimental medicine, Vol. 169, Issue 6, pp. 2233-8, (1989) (PubMed).

Edelman: "Cell adhesion molecules in the regulation of animal form and tissue pattern." in: Annual review of cell biology, Vol. 2, pp. 81-116, (1987) (PubMed).

Lanier, Le, Ding, Evans, Krensky, Clayberger, Phillips: "Expression of Leu-19 (NKH-1) antigen on IL 2-dependent cytotoxic and non-cytotoxic T cell lines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 138, Issue 7, pp. 2019-23, (1987) (PubMed).

Cunningham, Hemperly, Murray, Prediger, Brackenbury, Edelman: "Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing." in: Science (New York, N.Y.), Vol. 236, Issue 4803, pp. 799-806, (1987) (PubMed).

Hemperly, Murray, Edelman, Cunningham: "Sequence of a cDNA clone encoding the polysialic acid-rich and cytoplasmic domains of the neural cell adhesion molecule N-CAM." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 9, pp. 3037-41, (1986) (PubMed).

Lanier, Le, Civin, Loken, Phillips: "The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 136, Issue 12, pp. 4480-6, (1986) (PubMed).

Target Details for CD56

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Alternative Name: CD56 (NCAM1 Products)

Synonyms: CD56 antibody, MSK39 antibody, NCAM antibody, fj56g09 antibody, ncam antibody, ncam1 antibody, wu:fj56g09 antibody, NCAM1 antibody, n-cam antibody, E-NCAM antibody, NCAM-1 antibody, Ncam antibody, Cd56 antibody, N-CAM antibody, N-CAM-1 antibody, NCAM-C antibody, NCAMC antibody, N-CAM-1-B antibody, NCAM-1-B antibody, ncam1-a antibody, ncam1-b antibody, neural cell adhesion molecule 1 antibody, neural cell adhesion molecule 1a antibody, neural cell adhesion molecule 1 S homeolog antibody, neural cell adhesion molecule 1 L homeolog antibody, NCAM1 antibody, ncam1a antibody, ncam1 antibody, LOC100085373 antibody, ncam1.S antibody, Ncam1 antibody, ncam1.L antibody

Background: Synonyms: N-CAM