IL-4 antibody

Catalog No. ABIN2689765

Product Details anti-IL-4 Antibody

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-4 antibody is un-conjugated

Application: ELISA, Neutralization (Neut), Blocking Reagent (BR)

Brand: BD Pharmingen™

Characteristics: The OX-81 antibody reacts with rat interleukin-4 (IL-4). The immunogen used to generate this hybridoma was recombinant rat IL-4 protein. This is a neutralizing antibody. This antibody is routinely tested by ELISA capture. Other applications were tested during antibody development only or reported in the literature. Rat IL-4 ELISA Standard Curve.

BD Pharmingen™ Purified Mouse Anti-Rat IL-4 - Purified - Clone OX-81 - Isotype Mouse IgG1, κ - Reactivity Rat - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Recombinant rat IL-4 protein

Clone: OX

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-IL-4 antibody (ABIN2689765)

Ramírez, Fowell, Puklavec, Simmonds, Mason: "Glucocorticoids promote a TH2 cytokine response by CD4+ T cells in vitro." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 7, pp. 2406-12, (1996) (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Prigent, Saoudi, Pannetier, Graber, Bonnefoy, Druet, Hirsch: "Mercuric chloride, a chemical responsible for T helper cell (Th)2-mediated autoimmunity in brown Norway rats, directly triggers T cells to produce interleukin-4." in: The Journal of clinical investigation, Vol. 96, Issue 3, pp. 1484-9, (1995) (PubMed).

Saoudi, Simmonds, Huitinga, Mason et al.: "Prevention of experimental allergic encephalomyelitis in rats by targeting autoantigen to B cells: evidence that the protective mechanism depends on changes in the cytokine response and migratory ..." in: The Journal of experimental medicine, Vol. 182, Issue 2, pp. 335-44, (1995) (PubMed).

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL-4 (IL4 Products)

Synonyms: IL4 antibody, IL-4 antibody, BCGF-1 antibody, BCGF1 antibody, BSF-1 antibody, BSF1 antibody, Il-4 antibody, Il4e12 antibody, IL2 antibody, interleukin 4 antibody, IL4 antibody, Il4 antibody

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation