TBXA2R antibody (AA 51-150) (HRP)

Catalog No. ABIN2690013

This anti-TBXA2R antibody is a Rabbit Polyclonal antibody detecting TBXA2R in ELISA, IHC (p) and IHC (fro). Suitable for Human and Mouse.

Quick Overview for TBXA2R antibody (AA 51-150) (HRP) (ABIN2690013)

Target: TBXA2R (Thromboxane A2 Receptor (TBXA2R))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBXA2R antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TBXA2R Antibody (HRP)

Binding Specificity: AA 51-150

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TXA2R

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TBXA2R

Target: TBXA2R (Thromboxane A2 Receptor (TBXA2R))

Alternative Name: TXA2R

Background:

Synonyms: TXA2-R, BDPLT13, Thromboxane A2 receptor, Prostanoid TP receptor, TBXA2R

Background: Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase.

Gene ID: 6915

UniProt: P21731