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METTL14 antibody (AA 21-120) (Biotin)

METTL14 Reactivity: Human IHC (fro), IHC (p), WB Host: Rabbit Polyclonal Biotin
Catalog No. ABIN2690236
$418.77
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all METTL14 Antibodies
    METTL14 (Methyltransferase Like 14 (METTL14))
    Binding Specificity
    • 14
    • 6
    • 1
    • 1
    • 1
    AA 21-120
    Reactivity
    • 25
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 24
    • 1
    Rabbit
    Clonality
    • 24
    • 1
    Polyclonal
    Conjugate
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This METTL14 antibody is conjugated to Biotin
    Application
    • 13
    • 13
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Predicted Reactivity
    Mouse,Rat,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Mettl14
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C
    Expiry Date
    12 months
  • Target
    METTL14 (Methyltransferase Like 14 (METTL14))
    Alternative Name
    Mettl14 (METTL14 Products)
    Synonyms
    RGD1304822, G430022H21Rik, mKIAA1627, zgc:77296, methyltransferase like 14, methyltransferase like 14 L homeolog, Mettl14, mettl14.L, METTL14, mettl14
    Background

    N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop (By similarity). M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization (PubMed:24394384).

    Subcellular location: Nucleus

    Synonyms: mKIAA1627, G430022H21Rik, N6-adenosine-methyltransferase subunit METTL14, Methyltransferase-like protein 14, Mettl14, Kiaa1627

    Gene ID
    210529
    UniProt
    Q3UIK4
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