CD14 antibody

Catalog No. ABIN2704168

The Mouse Monoclonal anti-CD14 antibody is suitable to detect CD14 in samples from Human, Cynomolgus, Rhesus Monkey and Baboon. It has been validated for FACS.

Quick Overview for CD14 antibody (ABIN2704168)

Target: CD14

Reactivity: Human, Cynomolgus, Rhesus Monkey, Baboon

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: 26ic

Product Details anti-CD14 Antibody

Purpose: CD14 Unconjugated Antibody

Characteristics: The clone 26ic, a mouse monoclonal antibody, reacts with a human 53-55 kDa glycosylphosphatidylinositol (GPI)- anchored single chain cell surface antigen known as CD14. The CD14 expression is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. 26ic binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes.

Purification: Purified

Purity: >95 %

Immunogen: Cultured human peripheral blood monocytes

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD14

Target: CD14

Alternative Name: CD14

NCBI Accession: NM_000591

UniProt: P08571

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades