CD14 antibody (PerCP)

Catalog No. ABIN2704177

This Mouse Monoclonal antibody specifically detects CD14 in FACS. It exhibits reactivity toward Human, Cynomolgus, Rhesus Monkey and Baboon.

Quick Overview for CD14 antibody (PerCP) (ABIN2704177)

Target: CD14

Reactivity: Human, Cynomolgus, Rhesus Monkey, Baboon

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is conjugated to PerCP

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: 26ic

Product Details anti-CD14 Antibody (PerCP)

Purpose: CD14 PerCP Antibody

Characteristics: The clone 26ic, a mouse monoclonal antibody, reacts with a human 53-55 kDa glycosylphosphatidylinositol (GPI)- anchored single chain cell surface antigen known as CD14. The CD14 expression is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. 26ic binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes.

Purification: Purified

Purity: >95 %

Immunogen: Cultured human peripheral blood monocytes

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 12 μg/mL

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CD14

Target: CD14

Alternative Name: CD14

NCBI Accession: NM_000591

UniProt: P08571

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades