Transferrin Receptor antibody
Quick Overview for Transferrin Receptor antibody (ABIN2704329)
Target
See all Transferrin Receptor (TFRC) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- CD71 Unconjugated Antibody
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Characteristics
- The antibody is directed against the transferrin receptor (CD71), the 95 kDa, type II membrane glycoprotein. CD71is expressed on activated, but not resting lymphocytes, monocytes, macrophages, most dividing cells and on brain endothelium, and is upregulated during response to antigens and/or mitogens. The transferrin receptor binds Fe(Apo)-transferrin and via endocytosis and delivers iron required by the growing cell for cellular metabolism.
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Purification
- Purified
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Purity
- >95 %
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Immunogen
- Human acute lymphoblastic leukaemia cells
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Isotype
- IgG1, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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Alternative Name
- CD71
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NCBI Accession
- XM_011513112, NM_003234, NM_001128148
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UniProt
- P02786
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Pathways
- Transition Metal Ion Homeostasis
Target
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