Cyclin D1 antibody (pThr286)

Catalog No. ABIN7301540

This Rabbit Polyclonal antibody specifically detects Cyclin D1 in WB and IHC. It exhibits reactivity toward Human and Rat.

Quick Overview for Cyclin D1 antibody (pThr286) (ABIN7301540)

Target: Cyclin D1 (CCND1)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin D1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Cyclin D1 Antibody

Binding Specificity: pThr286

Purpose: Rabbit polyclonal antibody to Cyclin D1 (Phospho-T286)

Specificity: Recognizes endogenous levels of Cyclin D1 protein only when phosphorylated at T286.

Characteristics: Rabbit polyclonal antibody to Cyclin D1 (pT286)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding T286 of human Cyclin D1 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/100 - 1/200)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Cyclin D1

Target: Cyclin D1 (CCND1)

Alternative Name: Cyclin D1

Background: BCL1, PRAD1, G1/S-specific cyclin-D1, B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, PRAD1 oncogene

Gene ID: 595, 12443, 58919

UniProt: P24385

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling