PRAS40 antibody (pThr246)

Catalog No. ABIN7301480

The Rabbit Polyclonal anti-PRAS40 antibody (ABIN7301480) specifically detects PRAS40 in WB and IHC. The antibody is reactive with Human, Mouse, Rat and Cow samples.

Quick Overview for PRAS40 antibody (pThr246) (ABIN7301480)

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRAS40 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PRAS40 Antibody

Binding Specificity: pThr246

Purpose: Rabbit polyclonal antibody to PRAS40 (Phospho-T246)

Specificity: Recognizes endogenous levels of PRAS40 protein only when phosphorylated at T246.

Characteristics: Rabbit polyclonal antibody to PRAS40 (pT246)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding T246 of human PRAS40 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/50 - 1/100)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PRAS40

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Alternative Name: PRAS40

Background: PRAS40, Proline-rich AKT1 substrate 1, 40 kDa proline-rich AKT substrate

Gene ID: 84335, 67605

UniProt: Q96B36

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Autophagy, BCR Signaling, Warburg Effect