BTK antibody (pTyr223)

Catalog No. ABIN7299120

The Rabbit Polyclonal anti-BTK antibody is suitable to detect BTK in samples from Human, Mouse, Rat and Cow. It has been validated for WB and IF.

Quick Overview for BTK antibody (pTyr223) (ABIN7299120)

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTK antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-BTK Antibody

Binding Specificity: pTyr223

Purpose: Rabbit polyclonal antibody to BTK (Phospho-Y223)

Specificity: Recognizes endogenous levels of BTK protein only when phosphorylated at Y223.

Characteristics: Rabbit polyclonal antibody to BTK (pY223)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y223 of human BTK protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IF/IC (1/50 - 1/200)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BTK

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Alternative Name: BTK

Background: AGMX1, ATK, BPK, Tyrosine-protein kinase BTK, Agammaglobulinemia tyrosine kinase, ATK, B-cell progenitor kinase, BPK, Bruton tyrosine kinase

Gene ID: 695, 12229

UniProt: Q06187

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling