MEK1 antibody (pSer218, pSer222)

Catalog No. ABIN7299794

This anti-MEK1 antibody is a Rabbit Polyclonal antibody detecting MEK1 in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Rabbit, Chicken and Zebrafish (Danio rerio).

Quick Overview for MEK1 antibody (pSer218, pSer222) (ABIN7299794)

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Chicken, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MEK1 Antibody

Binding Specificity: pSer218, pSer222

Specificity: Recognizes endogenous levels of MKK1/2 (pS218/222) protein.

Characteristics: Rabbit polyclonal antibody to MKK1/2 (pS218/222)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MKK1/2.

Application Details

Application Notes: WB (1:500 - 1:1000), IH (1:100 - 1:200)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MEK1

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Alternative Name: MKK1/2

Target Type: Chemical

Background: MAP2K1, MEK1, PRKMK1, Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, MKK1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK 1, MAP2K2, MEK2, MKK2, PRKMK2, Dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK 2, ERK activator kinase 2, MAPK/ERK kinase 2, MEK 2

Gene ID: 5604, 5605, 26395

UniProt: Q02750, P36507, P31938, Q63932, Q01986, P36506

Pathways: MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling