SEC61B antibody (Center)

Catalog No. ABIN7298900

Cited in 1 publication. The Rabbit Polyclonal anti-SEC61B antibody (ABIN7298900) specifically detects SEC61B in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow and Dog samples.

Quick Overview for SEC61B antibody (Center) (ABIN7298900)

Target: SEC61B (Sec61 beta Subunit (SEC61B))

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC61B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SEC61B Antibody

Binding Specificity: Center

Purpose: Rabbit polyclonal antibody to SEC61B

Specificity: Recognizes endogenous levels of SEC61B protein.

Characteristics: Rabbit polyclonal antibody to SEC61B

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SEC61B. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/50 - 1/100)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SEC61B antibody (ABIN7298900)

Bolar, Golzio, Živná, Hayot, Van Hemelrijk, Schepers, Vandeweyer, Hoischen, Huyghe, Raes, Matthys, Sys, Azou, Gubler, Praet, Van Camp, McFadden, Pediaditakis, Přistoupilová, Hodaňová, Vyleťal et al.: "Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia. ..." in: American journal of human genetics, Vol. 99, Issue 1, pp. 174-87, (2017) (PubMed).

Target Details for SEC61B

Target: SEC61B (Sec61 beta Subunit (SEC61B))

Alternative Name: SEC61B

Background: Protein transport protein Sec61 subunit beta

Gene ID: 10952, 66212

UniProt: P60468

Pathways: Protein targeting to Nucleus