CDKN3 antibody

Catalog No. ABIN2718436

Product Details anti-CDKN3 Antibody

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDKN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Characteristics: Homo sapiens cyclin-dependent kinase inhibitor 3 (CDKN3), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human CDKN3(NP_005183) produced in HEK293T cell.

Clone: 2H1

Isotype: IgG2a

Application Details

Application Notes: WB 1:500, IHC 1:150, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CDKN3

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Alternative Name: CDKN3 (CDKN3 Products)

Synonyms: CDI1 antibody, CIP2 antibody, KAP antibody, KAP1 antibody, CDKN3 antibody, 2410006H10Rik antibody, K24G6.15 antibody, K24G6_15 antibody, KIP-RELATED PROTEIN 3 antibody, KRP3 antibody, inhibitor/interactor with cyclin-dependent kinase antibody, cyclin dependent kinase inhibitor 3 antibody, cyclin-dependent kinase inhibitor 3 antibody, inhibitor/interactor with cyclin-dependent kinase antibody, CDKN3 antibody, cdkn3 antibody, Cdkn3 antibody, ICK6 antibody

Background: The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 23.6 kDa

Gene ID: 1033

NCBI Accession: NM_005192

HGNC: 1033