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GRIN1/NMDAR1 antibody
GRIN1
Reactivity: Human, Rat, Mouse
WB, IF, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GRIN1/NMDAR1 Antibody
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Target
See all GRIN1/NMDAR1 (GRIN1) Antibodies
GRIN1/NMDAR1 (GRIN1)
(Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
Reactivity
All reactivities for GRIN1/NMDAR1 antibodies
Human, Rat, Mouse
Host
All hosts for GRIN1/NMDAR1 antibodies
Rabbit
Clonality
All clonalities for GRIN1/NMDAR1 antibodies
Polyclonal
Conjugate
All conjugates for GRIN1/NMDAR1 antibodies
This GRIN1/NMDAR1 antibody is un-conjugated
Application
All applications for GRIN1/NMDAR1 antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody detects endogenous levels of NMDAR1 protein.
Purification
Affinity-Chromatography using epitope-specific immunogen
Top Product
Discover our top product GRIN1 Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA: 1: 5000approx. 1: 10000. IF: 1: 50approx. 1: 200. IHC: 1: 50approx. 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for GRIN1/NMDAR1
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Target
GRIN1/NMDAR1 (GRIN1)
(Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
Alternative Name
NMDA Receptor 1 (GRIN1 Products )
Background
NMDA receptor subtypes of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. NMDAR1 plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission and is involved in the cell surface targeting of NMDA receptors.Synonyms: GRIN1, Glutamate [NMDA] receptor subunit zeta-1, NMDAR1
Molecular Weight
approx. 130 kDa
Gene ID
2902
NCBI Accession
NP_000823
UniProt
Q05586
Pathways
Synaptic Membrane , Feeding Behaviour , Regulation of long-term Neuronal Synaptic Plasticity
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