GATM antibody
Quick Overview for GATM antibody (ABIN2722035)
Target
See all GATM AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- Homo sapiens glycine amidinotransferase (L-arginine:glycine amidinotransferase) (GATM), nuclear gene encoding mitochondrial protein
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Purification
- Purified from mouse ascites fluids by affinity chromatography
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Immunogen
- Full length human recombinant protein of human GATM(NP_001473) produced in HEK293 cell.
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Isotype
- IgG1
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Application Notes
- WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
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Comment
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The concentration of the product may vary between diferrent lots.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5-1.0 mg/mL
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Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))
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Alternative Name
- GATM
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Background
- This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
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Molecular Weight
- 44.2 kDa
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Gene ID
- 2628
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NCBI Accession
- NM_001482
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HGNC
- 2628
Target
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