IL-6 antibody (AA 29-212)

Catalog No. ABIN2723733

This anti-IL-6 antibody is a Mouse Monoclonal antibody detecting IL-6 in WB, IHC and IF. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for IL-6 antibody (AA 29-212) (ABIN2723733)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 3G9

Product Details anti-IL-6 Antibody

Binding Specificity: AA 29-212

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 29-212 of human IL-6 (NP_000591) produced in E.coli.

Isotype: IgG2a

Application Details

Application Notes: WB 1:50000, IHC 1:50, IF 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-IL-6 antibody (ABIN2723733)

Hsu, Lai, Lee, Yen, Weng, Chen, Fang, Chen: "Mucin 2 silencing promotes colon cancer metastasis through interleukin-6 signaling." in: Scientific reports, Vol. 7, Issue 1, pp. 5823, (2019) (PubMed).

Theendakara, Peters-Libeu, Spilman, Poksay, Bredesen, Rao: "Direct Transcriptional Effects of Apolipoprotein E." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 36, Issue 3, pp. 685-700, (2016) (PubMed).

Target Details for IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Alternative Name: IL6

Molecular Weight: 23.5 kDa

Gene ID: 3569

NCBI Accession: NM_000600

HGNC: 3569

Pathways: TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome