KEAP1 antibody
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- Target See all KEAP1 Antibodies
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This KEAP1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Characteristics
- Homo sapiens kelch-like ECH-associated protein 1 (KEAP1), transcript variant 1
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinnt protein of human KEAP1(NP_987096) produced in HEK293T cell.
- Clone
- 1B4
- Isotype
- IgG1
- Top Product
- Discover our top product KEAP1 Primary Antibody
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- Application Notes
- WB 1:500~2000, IHC 1:150, FLOW 1:100,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate." in: The Journal of biological chemistry, Vol. 291, Issue 45, pp. 23719-23733, (2016) (PubMed).
: "MYD88 Expression and L265P Mutation in Mature B-Cell Non-Hodgkin Lymphomas." in: Genetic testing and molecular biomarkers, Vol. 19, Issue 7, pp. 372-8, (2015) (PubMed).
: "Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers." in: PLoS ONE, Vol. 9, Issue 2, pp. e88168, (2014) (PubMed).
: "Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 10, pp. 4913-20, (2014) (PubMed).
: "A reusable localized surface plasmon resonance biosensor for quantitative detection of serum squamous cell carcinoma antigen in cervical cancer patients based on silver nanoparticles array." in: International journal of nanomedicine, Vol. 9, pp. 1097-104, (2014) (PubMed).
: "Specific aquaporins facilitate Nox-produced hydrogen peroxide transport through plasma membrane in leukaemia cells." in: Biochimica et biophysica acta, Vol. 1843, Issue 4, pp. 806-14, (2014) (PubMed).
: "Regulation of human cytosolic sulfotransferases 1C2 and 1C3 by nuclear signaling pathways in LS180 colorectal adenocarcinoma cells." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 3, pp. 361-8, (2014) (PubMed).
: "Lipid rafts are required for signal transduction by angiotensin II receptor type 1 in neonatal glomerular mesangial cells." in: Experimental cell research, Vol. 324, Issue 1, pp. 92-104, (2014) (PubMed).
: "The globally disseminated M1T1 clone of group A Streptococcus evades autophagy for intracellular replication." in: Cell host & microbe, Vol. 14, Issue 6, pp. 675-82, (2013) (PubMed).
: "A PKG inhibitor increases Ca(2+)-regulated exocytosis in guinea pig antral mucous cells: cAMP accumulation via PDE2A inhibition." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 304, Issue 9, pp. G773-80, (2013) (PubMed).
: "Tracking protein aggregation and mislocalization in cells with flow cytometry." in: Nature methods, Vol. 9, Issue 5, pp. 467-70, (2012) (PubMed).
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Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate." in: The Journal of biological chemistry, Vol. 291, Issue 45, pp. 23719-23733, (2016) (PubMed).
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- Target
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
- Alternative Name
- KEAP1 (KEAP1 Products)
- Synonyms
- INrf2 antibody, KLHL19 antibody, INRF2 antibody, mKIAA0132 antibody, Inrf2 antibody, fb36f11 antibody, keap1 antibody, wu:fb36f11 antibody, KEAP1 antibody, klhl19 antibody, zgc:171654 antibody, kelch like ECH associated protein 1 antibody, kelch-like ECH-associated protein 1 antibody, Kelch-like ECH-associated protein 1 antibody, kelch-like ECH-associated protein 1a antibody, kelch like ECH associated protein 1 L homeolog antibody, kelch-like ECH-associated protein 1b antibody, KEAP1 antibody, Keap1 antibody, keap1a antibody, keap1 antibody, keap1.L antibody, keap1b antibody
- Background
- This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
- Molecular Weight
- 69.5 kDa
- Gene ID
- 9817
- NCBI Accession
- NM_203500
- HGNC
- 9817
- Pathways
- Maintenance of Protein Location
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