RUVBL2 antibody (AA 113-370)

Catalog No. ABIN2731260

Product Details anti-RUVBL2 Antibody

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Binding Specificity: AA 113-370

Reactivity: Human, Mouse, Rat, Dog, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This RUVBL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Characteristics: Homo sapiens RuvB-like 2 (E. coli) (RUVBL2)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragmengt corresponding to amino acids 113-370 of human RUVBL2(NP_006657) produced in E.coli.

Clone: 1A6

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for RUVBL2

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Alternative Name: RUVBL2 (RUVBL2 Products)

Background: This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.

Molecular Weight: 51 kDa

Gene ID: 10856

NCBI Accession: NM_006666

HGNC: 10856

Pathways: Telomere Maintenance