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SH2B3 antibody

SH2B3 Reactivity: Human WB, IHC, FACS, IF Host: Mouse Monoclonal 2D8 unconjugated
Catalog No. ABIN2731950
  • Target See all SH2B3 Antibodies
    SH2B3 (SH2B Adaptor Protein 3 (SH2B3))
    Reactivity
    • 25
    • 4
    • 3
    • 2
    Human
    Host
    • 22
    • 2
    • 2
    Mouse
    Clonality
    • 23
    • 2
    Monoclonal
    Conjugate
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH2B3 antibody is un-conjugated
    Application
    • 26
    • 13
    • 13
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    Characteristics
    Homo sapiens SH2B adaptor protein 3 (SH2B3)
    Purification
    Purified from mouse ascites fluids by affinity chromatography
    Immunogen
    Full length human recombinant protein of human SH2B3 (NP_005466) produced in HEK293T cell.
    Clone
    2D8
    Isotype
    IgG1
    Top Product
    Discover our top product SH2B3 Primary Antibody
  • Application Notes
    WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
    Comment

    The concentration of the product may vary between diferrent lots.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    SH2B3 (SH2B Adaptor Protein 3 (SH2B3))
    Alternative Name
    SH2B3 (SH2B3 Products)
    Synonyms
    LNK antibody, IDDM20 antibody, AI429800 antibody, Lnk antibody, SH2B adaptor protein 3 antibody, SH2B3 antibody, Sh2b3 antibody
    Background
    This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.
    Molecular Weight
    63 kDa
    Gene ID
    10019
    NCBI Accession
    NM_005475
    HGNC
    10019
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