SOCS3 antibody
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- Target See all SOCS3 Antibodies
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SOCS3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Characteristics
- Homo sapiens suppressor of cytokine signaling 3 (SOCS3)
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human SOCS3 (NP_003946) produced in HEK293T cell.
- Clone
- 3D3
- Isotype
- IgG2a
- Top Product
- Discover our top product SOCS3 Primary Antibody
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- Application Notes
- WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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Glycosylation-dependent interaction between CD69 and S100A8/S100A9 complex is required for regulatory T-cell differentiation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 5006-17, (2015) (PubMed).
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Glycosylation-dependent interaction between CD69 and S100A8/S100A9 complex is required for regulatory T-cell differentiation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 5006-17, (2015) (PubMed).
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- Target
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
- Alternative Name
- SOCS3 (SOCS3 Products)
- Synonyms
- socs3 antibody, fj09e12 antibody, zgc:56537 antibody, wu:fj09e12 antibody, MGC64393 antibody, MGC75749 antibody, xsocs3 antibody, MGC81248 antibody, atod4 antibody, cis3 antibody, cish3 antibody, socs-3 antibody, ssi-3 antibody, ssi3 antibody, SOCS3 antibody, ATOD4 antibody, CIS3 antibody, Cish3 antibody, SOCS-3 antibody, SSI-3 antibody, SSI3 antibody, Cis3 antibody, EF-10 antibody, Ef10 antibody, Ssi3 antibody, Socs-3 antibody, Ssi-3 antibody, suppressor of cytokine signaling 3a antibody, suppressor of cytokine signaling 3 S homeolog antibody, suppressor of cytokine signaling 3 antibody, suppressor of cytokine signaling 3 L homeolog antibody, socs3a antibody, socs3.S antibody, socs3 antibody, socs3.L antibody, SOCS3 antibody, Socs3 antibody
- Background
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
- Molecular Weight
- 24.6 kDa
- Gene ID
- 9021
- NCBI Accession
- NM_003955
- HGNC
- 9021
- Pathways
- JAK-STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
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