UCHL1 antibody

Catalog No. ABIN2745206

The Mouse Monoclonal anti-UCHL1 antibody has been validated for WB, IHC, ELISA, IF and IHC (fro). It is suitable to detect UCHL1 in samples from Human, Rat, Mouse, Cow, Pig, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio) and Sheep.

Quick Overview for UCHL1 antibody (ABIN2745206)

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Reactivity: Human, Rat, Mouse, Cow, Pig, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio), Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: This UCHL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 13C4

Product Details anti-UCHL1 Antibody

Specificity: Human UCHL1 / PGP9.5

Purification: Protein G purified

Immunogen: Native protein from brain.

Type of Immunogen: Native protein

Isotype: IgG2a kappa

Application Details

Application Notes: Approved: ELISA, IF (1 - 2 μg/mL), IHC, IHC-Fr (1 - 2 μg/mL), WB (0.5 - 1 μg/mL)

Usage: This antibody specifically reacts with a protein of 20-30  kDa, identified as UchL1 (Ubiquitin carboxyl-terminal hydrolase-1), or PGP9.5. Studies using UchL1 antibody have shown that expression is related to tumor progression, with high expression correlating with poor prognosis, making the protein a potentially useful marker for pancreatic and invasive colorectal cancer. A mutation in gene is believed to cause a form of Parkinson's disease. ELISA: Order BSA-free format for coating.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C to 8°C.

Target Details for UCHL1

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Alternative Name: UCHL1 / PGP9.5

Background: Name/Gene ID: UCHL1
Subfamily: Cysteine C12
Family: Protease

Synonyms: UCHL1, Ubiquitin C-terminal hydrolase, PARK5, PGP9.5, PGP95, Ubiquitin thioesterase L1, Neuron cytoplasmic protein 9.5, PGP 9.5, Uch-L1

Gene ID: 7345

Pathways: Feeding Behaviour