CARD11 antibody (N-Term)

Catalog No. ABIN2745520

The Rabbit Polyclonal anti-CARD11 antibody (ABIN2745520) specifically detects CARD11 in WB, IHC and ICC. The antibody is reactive with Human and Mouse samples.

Quick Overview for CARD11 antibody (N-Term) (ABIN2745520)

Target: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-CARD11 Antibody

Binding Specificity: AA 1-221, N-Term

Specificity: Recognizes human and mouse CARMA1. Detects a band of ~130Dka by Western blot.

Cross-Reactivity: Human, Mouse (Murine)

Immunogen: N-terminal human CARMA1 (aa 1-221 containing the CARD domain).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for CARD11

Target: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Alternative Name: CARMA1

Background: CARMA1 is involved in the costimulatory signal essential for T cell receptor (TCR)-mediated T cell activation. Its binding to DPP4 induces T cell proliferation and NF-kappaB activation in a T cell receptor/CD3-dependent manner. CARMA1 activates NF-kappaB via Bcl10 and IKK.

UniProt: Q9BXL7

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling