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CARD11 antibody (AA 985-1154)

CARD11 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6137939
  • Target See all CARD11 Antibodies
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    Binding Specificity
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 985-1154
    Reactivity
    • 33
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 31
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 33
    • 1
    Polyclonal
    Conjugate
    • 27
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD11 antibody is un-conjugated
    Application
    • 26
    • 11
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    AKTLVQRLLN SGGAMEFTIC KSDIVTRDEF LRRQKTETII YSREKNPNAF ECIAPANIEA VAAKNKHCLL EAGIGCTRDL IKSNIYPIVL FIRVCEKNIK RFRKLLPRPE TEEEFLRVCR LKEKELEALP CLYATVEPDM WGSVEELLRV VKDKIGEEQR KTIWVDEDQL
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 985-1154 of human CARD11 (NP_115791.3).
    Isotype
    IgG
    Top Product
    Discover our top product CARD11 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    Alternative Name
    CARD11 (CARD11 Products)
    Synonyms
    BENTA antibody, BIMP3 antibody, CARMA1 antibody, PPBL antibody, 0610008L17Rik antibody, 2410011D02Rik antibody, CARD11 antibody, LOC100232755 antibody, caspase recruitment domain family member 11 antibody, caspase recruitment domain family, member 11 antibody, caspase recruitment domain-containing protein 11 antibody, CARD11 antibody, Card11 antibody, LOC100550812 antibody, card11 antibody
    Background
    The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.,CARD11,BENTA,BIMP3,CARMA1,IMD11,PPBL,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,CARD11
    Molecular Weight
    133 kDa
    Gene ID
    84433
    UniProt
    Q9BXL7
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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