SIGLEC7 antibody

Catalog No. ABIN2749061

This Mouse Monoclonal antibody specifically detects SIGLEC7 in FACS. It exhibits reactivity toward Human.

Quick Overview for SIGLEC7 antibody (ABIN2749061)

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIGLEC7 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 6-434

Product Details anti-SIGLEC7 Antibody

Purpose: Anti-Hu CD328 Purified

Cross-Reactivity (Details): Human

Characteristics: The mouse monoclonal antibody 6-434 recognizes an extracellular epitope of CD328 (Siglec-7), a 75 kDa transmembrane glycoprotein expressed mainly on NK cells, dendritic cells and monocytes.

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: human dendritic cells

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for SIGLEC7

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Alternative Name: CD328

Background: Sialic acid binding Ig like lectin 7,CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells.,SIGLEC7, p75/AIRM1, D-siglec

Gene ID: 27036

UniProt: Q9Y286