CD56 antibody
Quick Overview for CD56 antibody (ABIN2749071)
Target
See all CD56 (NCAM1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Hu CD56 Purified
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Cross-Reactivity (Details)
- Human
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Characteristics
- The mouse monoclonal antibody LT56 recognizes an extracellular epitope of CD56 (NCAM), a transmembrane glycoprotein expressed ubiquitously in the nervous system and found also on T cells and NK cells.
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Purification
- Purified by protein-A affinity chromatography.
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Purity
- > 95 % (by SDS-PAGE)
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Immunogen
- Cell line KG1a
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Isotype
- IgG2a, kappa
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Application Notes
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Western blotting: Non-reducing conditions.
Flow cytometry: Recommended dilution: 1-4 μg/mL -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Do not freeze
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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Alternative Name
- CD56
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Background
- Neural cell adhesion molecule 1,CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.,NCAM1, MSK39
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Gene ID
- 4684
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UniProt
- P13591
Target
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